Hyaluronic Acid

Hyaluronic acid research has existed for over 40 years now. Research has shown that a good dose is 200 mg. taken dividedly each day. Medical researchers have also called it hyaluronan or hyaluronate. They have discovered that hyaluronic acid is actually found naturally in many tissues of your body like the skin, the cartilage and the vitreous humor. The first biomedical product ever developed from hyaluronic acid was approved for use in opthalomological applications for cornea transplant, cataract surgery, glaucoma surgery and retinal attachment surgery.

Research on hyaluronic acid has actually been very successful. Products derived from hyaluronic research have been approved by the Food and Drug Administration (FDA) since 2003. This acid is used to monitor the progression of certain diseases. It is used as a tumor marker for prostate and breast cancer. It has been used as a food supplement to enhance the knee joints and treat osteoarthritis and to induce tissue healing after cataract surgery. In addition, it has been proven to be good for the skin.

Hyaluronic acid can now be used to work through several mechanisms of action. It can restore normal synovial fluid with improved viscoelasticity, improve the effects of cartilage biosynthesis and degradation as well as anti-inflammatory effects and direct analgesic effects. This is the most important effect it has for athletes. You can use it to protect the synovial fluid in the knee and help treat osteoarthritis. Effects are induced by injecting the acid into the knee.

Hyaluronic acid can also be converted into powder form and applied as a cosmetic ingredient. It is the next generation anti-aging supplement that can help give you healthier skin texture, resulting in a more moisturized and younger appearance. It can remedy facial wrinkles. It works in the same manner as collagen injections but has a longer lasting effect with fewer allergic reactions.

Hyaluronic acid, a key component of human tissue, aiding the body’s flexibility, mobility and moisture retention is a popular component of many anti-aging products but can also provide a wealth of benefits in the medical sphere. Recently, in an attempt to find effective treatment methods for arthritis, scientists have found a strong association between levels of Hyaluronic acid and severe knee and hip arthritis known as osteoarthritis or OA.

The study, conducted by researches from the University of North Carolina at Chapel Hill and Duke University Medical Center, utilized a diverse subject base of blood samples from 753 white and black American men and women. This research is part of the hope that early identification and intervention can improve outcomes for people with OA, a common cause of pain and disability among older Americans. The findings suggest that measuring levels of Hyaluronic acid could allow doctors to help prevent joint destruction before it can be measured on an X-ray image.
In a similar vein, Hyaluronic acid injections have been prescribed by doctors for over 20 years as a method for treating osteoarthritis of the knee. Hyaluronic acid is thought to restore elasticity to the synovial fluid that surrounds the knee joint, which is depleted in patients with osteoarthritis of the knee. However, there is continued debate as to the efficacy of these treatments. Recently, French researchers compared the safety and effectiveness of the NRD101 Hyaluronic acid knee injection with an orally administered drug, Diacerein, shown by past research to have a structural benefit in hip osteoarthritis.

Three hundred one patients were randomly assigned to receive three courses of NRD101 injections, each involving one injection weekly for three weeks, every three months, along with a placebo capsule; placebo injections and diacerein twice daily; or placebo injections and capsules. Symptoms were evaluated both by patients and clinicians, and X-rays were performed to evaluate the effects of treatment on the knee structure at the beginning and end of the study. Patients in all three groups reported improvement of their symptoms and few patients dropped out of the study, which suggests injections are a feasible approach to treating knee osteoarthritis. However, the doctors did conclude that further studies were needed to evaluate other treatment approaches using this route of administration.

Furthermore, based on research by the publication American Family Physician, although clinical experience and studies of available Hyaluronic acid injection products including hyaluronan and hylan G-F 20, are inconclusive, they appear to produce beneficial effects with minimal adverse reactions in a significant number of patients. Thus, although research is ongoing into the benefits of Hyaluronic acid knee injections, it is clear that the injections are at present a viable alternative to orally administered arthritis relief.